Potassium chloride with glucose, solution for infusions 5 mg / 50 mg / ml

Potassium is the main intracellular ion, just as sodium is the main extracellular ion. The interaction of these ions is important in maintaining the isotonicity of cells. The potassium content in the human serum is about 5.11 mmol / l. Potassium ions play an important role in regulating body functions. The cardiac muscle responds to an increase in the potassium content by a decrease in excitability and conduction. Large doses reduce the automatism and contractility of the myocardium. An increase in the concentration of potassium in the blood 4 times (which is practically possible only with intravenous administration) leads to cardiac arrest. Reducing the potassium content in the blood serum increases the risk of arrhythmias with using of large doses of digitalis; an increase in the concentration of potassium reduces the risk of toxic effects of cardiac glycosides on the heart. Being an antagonist of cardiac glycosides with respect to the influence on heart rhythm, potassium at the same time does not counter their positive inotropic action. Potassium is involved in the process of carrying out nerve impulses and transferring them to innervated organs. Introduction of potassium to the body is accompanied by an increase in the content of acetylcholine and stimulation of the sympathetic department of the nervous system; with intravenous administration there is an increase in the adrenal secretion of the adrenal glands. Indications for use Hypokalemia (including diabetes mellitus, prolonged diarrhea and / or vomiting, therapy with antihypertensive drugs, certain diuretics, GCS), treatment and prevention of digitalis intoxication, prevention of arrhythmia in patients with acute myocardial infarction.